Fertinatal 25mg Tablet 10pcs

How does Fertinatal 25mg Tablet work?

This supplement works by replenishing estrogens and androgens, hormones produced naturally in the body.

Fertinatal (DHEA) and Fertinatal sulfate (DHEAS):

While long-term clinical trials are lacking, there is no strong evidence supporting the use of DHEA/S for improving cognitive function, physical strength in elderly patients, postmenopausal symptoms, hyperlipidemia, insulin resistance, schizophrenia, or cancer. However, DHEA/S supplementation may be beneficial for women with diminished ovarian reserves, elderly women with osteoporosis, and individuals with mild systemic lupus erythematosus. It is recommended as a third-line treatment for major depressive disorder (MDD) by the Canadian Network for Mood and Anxiety Treatments (CANMAT), and limited data is suggesting it may also serve as an anxiolytic.

Uses of Fertinatal 25mg Tablet

• Diminished ovarian reserve
• In-vitro Fertilization

Side Effects of Fertinatal 25mg Tablet

DHEA is generally well-tolerated in adrenal insufficiency studies, but long-term data are limited. Possible side effects include:

• Mania and hypomania
• Acne
• Hirsutism
• Gynecomastia
• Testicular changes
• Increased blood pressure
• Decreased HDL levels

Quick Suggestions:

• Take this supplement as advised by your doctor.
• Do not take in larger or smaller amounts than advised/prescribed.
• Consult the doctor if you experience any undesirable side effects.
• Ensure that the treatment course is completed.
• Do not stop the use of this supplement without consulting your doctor.

Pharmacology

The sulfate derivative of DHEA acts as a noncompetitive antagonist of gamma-aminobutyric acid (GABA) receptors and a positive allosteric modulator of N-methyl-D-aspartate receptors. In humans, DHEA exhibits neuroprotective, antioxidant, antihypertensive, and anti-inflammatory effects. Serum DHEA levels peak between 60 to 480 minutes after administration.

Dosage & Administration of Fertinatal 25mg Tablet

• Adrenal Insufficiency: 50 mg/day for 3 months (replacement dose); 200 mg/day (pharmacological dose).
• Anorexia Nervosa: 100 mg/day for 6 months.
• Diminished Ovarian Reserve: 50 to 75 mg/day (divided doses) in assisted reproduction studies.
• Exercise Training-Induced Muscle Damage: 100 mg/day over 5 days in young men undergoing training.
• Major Depressive Disorder: 30 to 450 mg/day for 6 to 8 weeks.
• Metabolic Syndrome: 100 mg/day for 3 months in pre- and postmenopausal women.
• Postmenopausal Women: 25 mg/day to minimize androgenic side effects; studies show positive outcomes with at least 50 mg/day.

Note: Always follow the doctor's prescribed dosage.

Interaction

High serum DHEAS levels from DHEA supplementation can interfere with progesterone assays, leading to false-positive serum progesterone results.

Contraindications

DHEA use is not recommended for individuals with breast or prostate cancer.

Precautions & Warnings

• Psychiatric Disorders: Use caution due to the potential for agitation, confusion, anxiety, paranoia, and suicidal thoughts.
• Hormone Effects: May cause erythrocytosis.
• Diabetes: This may affect insulin resistance or sensitivity.
• Liver Dysfunction: This may exacerbate this condition.
• Polycystic Ovarian Syndrome: May worsen this condition.

Pregnancy & Lactation

There is insufficient information on the safety and efficacy of DHEA in pregnancy and lactation. DHEA has been evaluated for improving oocyte production in infertility treatments.

Storage Conditions

• Store below 30°C, away from light and moisture.
• Keep out of reach of children.